Sangeeta Shrotriya, Mohammad S Ali, Achinto Saha, Sitesh C Bachar, Lam Md S Islam.
Anti-inflammatory and analgesic effects of Hedychium coronarium Koen
Pak J Pharm Sci Jan 2007;20(1):47-51.
University of Dhaka, Dhaka, Bangladesh
Successive hexane, chloroform and methanol extracts of the rhizome of Hedychium coronarium Koen. (HC) were subjected to evaluate analgesic and anti-inflammatory activities in animal model. In acetic acid-induced writhing test, the chloroform and methanol extract at doses of 400 mg/kg body weight elicited 27.23 and 40.59% inhibition of writhing reflex respectively. Both the chloroform and methanol extracts showed significant elongation of tail flick time (41.15 and 61.32% elongation respectively) at 400 mg/kg body weight. In carrageenan induced rat paw edema test, the chloroform and methanol extracts at a dose of 400 mg/kg body weight showed statistically significant (P<0.01) inhibition of paw edema by 27.46 and 32.48%, respectively at the third hour after carrageenan injection.
Category: Alternative Medicine
Keywords: Analgesia. Hedychium Coronarium Koen. Rats. Animals.
Click here for Full Text Article
This article has been viewed 301 times
Download in Citation Manager - Print - Email - PakMediNet Member Services Submit your Research Synopsis for Free Expert analysis - Search- Feedback - Drug Index
Post and View Comments on this Article
