Aqueel Hussain Pabaney, Murad Moosa Khan, Haq Nawaz, Rustam Khan.
Interferon α – induced psychotic disorder in a patient with chronic hepatitis B
Med Today Mar 2007;5(1):28-30.
Aga Khan University Hospital, Karachi

Interferon has remained the mainstay for treating patients suffering from chronic viral hepatitis. However, its efficiency has been limited by the neuropsychiatric side effect profile that it carries; neurotransmitter alterations in the central nervous system (CNS) have been correlated to psychiatric complications of Interferon α. Although mood disorders such as depression occasionally develop during Interferon α therapy, psychotic disorders have been rarely reported. We present a case of Interferon α 2b induced psychotic symptoms in a young male with hepatitis B and review the relevant literature.

Category: Case Reports
Keywords: Interferon. Hepatitis. Psychosis. Hepatitis B.

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