Muhammad Zubair, Muhammad Ali Channa, Masoom Raza Mirza, Lubna Habib.
Is biopsy needed in every gastritis found during endoscopy?
Pak J Med Sci Oct - Dec 2009;25(5):849-51.
Hamdard Medical University Hospital, Karachi

Objective: To find out concordance between endoscopic and histological diagnosis of gastritis in dyspeptic patients. Methodology: All dyspeptic patients who underwent upper gastrointestinal endoscopy with endoscopic diagnosis of gastritis and available biopsy report from July 2006 to June 2008 in Hamdard Medical University Hospital and different private hospitals of Karachi were included in this study. The endoscopist formed a global impression on the presence or otherwise of gastritis according to the Sydney System. Patients with ulcer, growth and any other endoscopic diagnosis apart from gastritis were excluded. With standard biopsy forceps, minimum of two gastric biopsies from inflamed mucosa were taken for histological evidence of gastritis. Results: Total 112 patients (44 males and 68 females) were included in the study with mean age of 41.95 years. Most common symptom experienced by patients was epigastric discomfort in 103 (92%) of patients. In all patients endoscopic diagnosis was gastritis. Biopsy reports showed chronic gastritis in 109 (97.3%) patients. Conclusion: There is good concordance of endoscopic findings of gastritis with histological evidence of gastritis and thus biopsy is not required in every case of gastritis.

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