Syed Sohail Tanvir, Sameeh J Khan.
Spectrum of gastrointestinal pathology in chronic renal failure patients
J Pak Inst Med Sci Jul 2004;15(1):839-44.
Department of Nephrology, Pakistan Institute of Medical Sciences, Islamabad

A total of 168 cases of chronic renal failure who had GI symptoms were investigated by endoscopic examination for upper GI lesions. Age ranged from 21 to 65 years with a mean age of 40.3 years. Male: female ratio was 1.85:1. Aetiologically CRF was most commonly due to diabetes mellitus (30.9%), followed by chronic glomerulonephritis (23.2%), membranoproliferative GN (13.1%), membranous GN (4.8%), focal segmental GN (4.2%), and other lesions. Dyspepsia, heart burn, nausea, anorexia and abdominal distension were common GI symptoms. On endoscopy, esophageal involvement was seen in 46%, gastric lesions in 27% and duodenal involvement in 15% of cases. Esophagitis, gastritis and duodenitis together were observed in 3% of cases.

Category: Nephrology
Keywords: Renal Failure. Esophagitis. Duodenitis. Dyspepsia.

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Posted by: ntarif on Jul 2005

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