Khalid A Sheikh, Saringat Hj Baie, Gul Majeed Khan.
Haruan (Channa Striatus) incorporated palm-oil creams: formulation and stability studies
Pak J Pharm Sci Jan 2005;18(1):1-5.
International Medical University, 57000, Kuala Lumpur, Malaysia
Topical emulsions stabilized with non-ionic emulsifiers have been an attractive alternative as vehicles for drug delivery, particularly for the patients suffering from dermatological problems. Haruan (a natural wound healer) creams were formulated with different types of emulsifiers (Tween 80 and Span 80) using different grades of Malaysian Palm-oleins (DFPL 56, 60, 62 and 65). The stability (at room temperature and accelerated stability testing) of the various creams was evaluated at different temperatures (5, 25 and 45oC) for a period of 6 months by measuring changes in droplet size, viscosity and percentage oil separation. The emulsifier type and concentration showed pronounced effect on the physicochemical properties of the cream, whereas storage time did not. This study suggested that the choice of emulsifiers and concentration of haruan extract are the most important factors in the stability of the haruan creams.
Category: Pharmacology
Keywords: Haruan. Channa Striatus. Palm Oil. Nutrition.
Click here for Full Text Article
This article has been viewed 462 times
Download in Citation Manager - Print - Email - PakMediNet Member Services Submit your Research Synopsis for Free Expert analysis - Search- Feedback - Drug Index
Post and View Comments on this Article
