Ejaz Butt, Saeed A Khan, Naseer A Chaudrhy, Qureshi G R.
Intra-cranial space occupying lesions - a morphological analysis
Biomedica Jan - Jun 2005;21(1):31-5.
Postgraduate Medical Institute, Lahore

The purpose of this study was to provide preliminary data on morphological patterns of intracranial space occupying lesions (ICSOL) in central Punjab province. This is a cross-sectional prospective study on 100 consecutive cases of intra-cranial space occupying lesions admitted to both the neurosurgery units of Lahore General Hospital, Lahore, Pakistan. The biopsy materials were examined histologically using paraffin sections. Eighty nine (89) patients had neoplasms, while eleven (11) had non-neoplastic lesions. Neuroepithelial tumours comprised 41% of all the neoplasms, followed by meningiomas being 23%, schwannomas 11% and metastatic tumours 6%. Males were affected slightly more than females (1.17:1). Tuberculomas constituted 3% of the lesions. It was concluded that age and sex distribution were generally comparable to the other published literature. Similarly neuroepithehal tumours formed majority of the lesions. However meningiomas had a higher frequency as compared to the western literature; moreover tuberculomas should also be considered in the differential diagnosis of such lesions in this part of the world.

Category: Neurology
Keywords: Brain Tumors. Cancer. Tuberculoma.

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