Ghazanfar Ali Sirhindi, Shahida Amjad Riaz Shah, Muhammad Javed Asif, Mateen Izhar.
Coagulation profile in male albino rats fed on Nigella sativa and aspirin for six weeks duration
Ann King Edward Med Coll Oct - Dec 2004;10(4):432-3.
Department of Pathology, Shaikh Zayed Hospital, Lahore

In this study ninety male albino rats were selected and were divided into six groups on the basis of different diets given. Control group (I) was fed on synthetic diet and experimental groups (IIA, IIB, IIC, IID and IIE) were fed on I mg aspirin, 15 mg, 30 mg, 45 mg Nigella sativa per kg body weight respectively while HE was given 30 mg Nigella sativa and I mg aspirin/kg body weight. Blood samples were collected by heart puncture and coagulation parameters were done. BT was prolonged in groups taking aspirin only. APTT was reduced significantly in groups taking different concentrations of Nigella sativa when compared with the control. Percentage of clot retraction was weak significantly in groups taking aspirin only when compared with other groups of male albino rats.

Category: Pathology
Keywords: Clotting Factors. Coagulation. Aspirin. Nigella Sativa. Rats. Animals.

Click here for Full Text Article

This article has been viewed 370 times

Submit your Research Synopsis for Free Expert analysis - Search- Feedback - Drug Index
Post and View Comments on this Article