Gul Muhammad, Abdul Salam Khan Gandapur, Darya Khan, Muhammad Tayyab, Misal Khan.
The role of Surgery in Homozygous Beta-Thalassaemia
J Ayub Med Coll Abottabad Apr - Jun 2000;12(2):19-20.
Frontier Medical College, Abbottabad

Background: Various Strategies are adopted for the control and management of thalassaemia. Despite advances in the medical management of thalassaemia there remains a definite place for splenectomy in the management of thalassaemia, particularly in a developing country like Pakistan. Methods: The Surgical aspects of the management of patients with homozygous beta-thalassaemia are reviewed, and operative findings in 15 patients with the disease who were subjected to splenectomy are described. Results: Postoperatively frequency of blood transfusion was reduced for maintaining the haemoglobin level, due to decreased blood consumption. The age range was from 12-13 years. Hepatomegaly was present in all the cases. In 73 percent cases hyperplastic lymph nodes containing erythropoetic elements were found. Cholelethiasis was seen in only one case. The recovery was smooth in 10 (67%) cases. Wound infection developed in 2 cases. Pneumonia occurred in only one case. Two patients developed fever and one items which responded to conservative treatment.

Category: Haematology
Keywords: Beta-Thalassemia. Thalassemia.

Click here for Full Text Article

This article has been viewed 749 times

Submit your Research Synopsis for Free Expert analysis - Search- Feedback - Drug Index
Post and View Comments on this Article