Tayyaba Batool, Jamshed Akhtar, Soofia Ahmed, Atif Saeed, Shazia Jalil, Aqil Soomro.
Comparative study of different drug treatment protocols in patients with peritonitis
J Surg Pak Sep 2005;10(3):11-3.
National Institute of Child Health Karachi

Objective: To compare two treatment protocols for patients with peritonitis. Design: A comparative study. Place and duration: The study was conducted at Surgical Unit B, National Institute of Child Health, Karachi, during the year 2002. Patients and Method: A total of 35 patients were included in the study. Two groups were made. In-group 1(n=15), protocol I (ampicillin, gentamicin & metronidazole - AGM) was used and in-group 2(n=20), protocol II (ceftazidime & metronidazole - CM) was used. All patients admitted with the diagnosis of peritonitis were recruited into the study and randomly grouped. Results: The most common cause of peritonitis in both the groups was perforated appendicitis. Majority of the patients (n-27) were above 5 years of age. Wound infection was the commonest complication observed in both the groups (n-6 in group I and n-3 in group 2). E.coli was the commonest isolate in both the groups. Mean hospital stay in group I was 12 days and in group 2, nine days. No significant difference was observed as regard to outcome in terms of disease control and complications, while logistics in use of giving drugs made a difference in favor of group IL Mean cost of drug treatment was Rupees 1980 in group I and Rupees 1620 in group 2. Conclusion: Both protocols can be used depending upon availability of drugs and logistics.

Category: Surgery
Keywords: Peritonitis.

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