Tariq Butt, Muhammad Salman, Rifat Nadeem Ahmad, Syed Yousaf Kazmi.
In vitro activity of ciprofloxacin and sparfioxacin against Streptococcus pneumoniae
Pak J Pathol Jan - Mar 2004;15(1):8-10.
Armed Forces Institute of Pathology, Rawalpindi
The in vitro activity of ciprofloxacin and sparfloxacin was compared against seventy clinical isolates of Streptococcus pneumoniae from Rawalpindi/Islamabad region. The Minimum Inhibitory Concentrations (MICs) of the isolates were determined by agar dilution method. All the isolates were susceptible to sparfioxacin while 48% of the isolates were resistant to ciprofloxacin. The antibacterial concentration of sparfloxacin (MIC90 0.25 ug/ml) was significantly lower than that of ciprofloxacin (MIC90, 2 ug/ml). Sparfloxacin has excellent in vitro activity against Streptococcus pneumoniae.
Category: Microbiology
Keywords: Sparfloxacin. Ciprofloxacin. Streptococcus Pneumoniae.
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