Azizur Rahman, Shahnawaz Channa, Jawaid Hassan Niazi, Muhammad Saleh Memon.
Dacryocystorhinostomy without intubation with intraoperative Mitomycin-C
J Coll Physicians Surg Pak Jul 2006;16(7):476-8.
AlIbrahim Eye Hospital, Malir City, Karachi
Objective: To evaluate the success rate and complications of intraoperative Mitomycin-C in dacryocystorhinostomy (DCR) surgery. Study Design:Quasi-experimental study. Place and Duration of Study: Isra postgraduate institute of Ophthalmology, Al-Ibrahim Eye Hospital, Malir, Karachi, from January 2003 to December 2004. Patients and Methods: This study included total 90 eyes of 90 patients fulfilling the inclusion criteria.The surgical procedure of external DCR done with intraoperative Mitomycin-C with a neurosurgical cottonoid soaked with 0.2mg/ml. Mitomycin C was applied to the anastomosed flaps and osteotomy site for 10 minutes, without Silicon tube intubation. Surgery was done under local as well as general anesthesia. Patients were followed for 6 months. Results: Out of 90 patients included in this study, only 2 patients complained of persistent epiphora after 6 months follow-up and were labeled as failed DCR. Remaining 88 had either no tearing or significant improvement of tearing after 6 months follow up and patent lacrimal system by syringing without pressure. Success rate in this procedure was 97.77% (p-value< 0.001). This study showed very high rate of success. Only complication noted was excessive nasal bleeding which was easily controlled. Conclusion: Intraoperative Mitomycin-C application in external DCR is safe, effective, cheap adjunct that helps to achieve good results of DCR surgery.
Category: Eye
Keywords: Epiphora. Dacryocystorhinostomy. Mitomycin C. Lacrimal Apparatus.
Click here for Full Text Article
This article has been viewed 328 times
Download in Citation Manager - Print - Email - PakMediNet Member Services Submit your Research Synopsis for Free Expert analysis - Search- Feedback - Drug Index
Post and View Comments on this Article
