Ruhila Hanif, Abdus Sattar, Iftikhar Qayum.
FBG and TC/HDL Ratios in Type 2 Diabetes Mellitus
J Ayub Med Coll Abottabad Apr - Jun 2001;13(2):42-4.
Ayub Medical College, Abbottabad
Background: Presence of dyslipidemia, i.e. raised Total Cholesterol (TC) and decreased High Density Lipoproteins (HDL) is an established phenomenon in type 2 diabetes mellitus. Its relationship to the fasting blood sugar (FBG) level in both diabetics and non-diabetics has yet to be established. The present study aims to show such a relationship. Methods: 150 subjects were selected and divided into two groups, one of 50 controls (non-diabetics), the other of 100 patients with type 2 diabetes mellitus. Their FBG levels were determined by enzyme oxidase method, and their TC and HDL levels were determined using a standard kit method. Results: FBG and TC:HDL ratios were increased in the patient group (p = <0.001). Comparison of FBG and TC:HDL ratios revealed a highly significant rise (p = <0.001) in the patient group. FBG with TC:HDL ratios between both groups showed a positive correlation (r = 0.554). Conclusion: The results of the present study suggest an association between FBG and TC:HDL ratios, which may be a contributory factor to the increased prevalence of coronary artery disease in patients with type 2 diabetes mellitus.
Category: Internal Medicine
Keywords: Fasting Blood Glucose. HDL. Cholesterol. Lipoproteins. Diabetes Mellitus.
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