Epigenetics to shape stem cell future

Epigenetics to shape stem cell future
Everyone hopes that one day stem cell-based regenerative medicine will help repair diseased tissue. Before then, it may be necessary to decipher the epigenetic signals that give stem cells their unique ability to self-renew and transform them into different cell types.

The hype over epigenetic research is because it opens up the possibility of reprograming cells. By manipulating epigenetic marks, cells can be transformed into other cell types without changing their DNA. It is simply a question of adding or removing the chemical tags involved.

Stem cells rely heavily on epigenetic signals. As a stem cell develops, chemical tags on the DNA or its surrounding histone proteins switch genes on or off, controlling a cell’s fate.

European labs are breaking ground in both the epigenetic and stem cell arenas. To build on this expertise and stimulate the exchange on novel technologies.


Epigenetic research has benefited tremendously from genome technology, and work in the field is advancing at break-neck speed. “If you think that the first enzymes controlling histone methylation were found in 2001, the acceleration is tremendous.

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Aftab ahmad

Posted by: aftabacPosts: 271 :: 23-02-2007 :: | Reply to this Message