Abolhassan Seyedzadeh, Mitra Hemmati, Simin Gheiny.
Henna induced severe hemolysis: In glucose 6 phosphate dehydrogenase deficiency.
Pak J Med Sci Jan ;23(1):119-21.

Glucose– 6–phosphate dehydrogenase deficiency is one of the most common enzyme deficiencies worldwide. Lawsone is a chemical present in henna, the crushed leaves of which are not only used as a cosmetic agent but also as a therapeutic agent for some types of skin lesion. In vitro observations indicated that lawsone is an agent capable of causing oxidative hemolysis. We report a 42 – days old G6PD – deficient male infant with acute severe hemolysis after application of henna to treat his napkin dermatitis.

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