Muhammad Aslam Memon.
Drug fever – a hospital based study.
Pak Paed J Jan ;30(3):142-6.

Objective: To study the frequency, causative agents, symptomatology of drug fever in children Study design: A hospital based descriptive study. Place and duration of study: The study was carried out from Jan 01,2005 to Dec 31,2005. All children examined by author were included, both in private and public sector hospitals at Hyderabad. Subjects and method: Children 1 to 12 years of age with febrile illness of more than 10 days duration and prior use of drugs for at least 5-7 days were included in this study and were evaluated for having drug fever. Results: 62(0.72% of total 8560) febrile children, 32 of them males and 30 females, were diagnosed as having drug fever, with Cephalosporins being the common group responsible for causing fever in 33(53.22%) followed by penicillins in 14(22.60%), antituberculous in 12(19.35%),Phenytoin in 2(3.2%) and carbamezapine in 1(1.61%). Conclusion: 1) Drugs should be considered as a cause of fever of obscure origin. 2) Judicious use of drugs especially antibiotics can not be over emphasized.

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