Saba A Sattar, Nadeem Hameed, Sajid Maqbool.
Incidence and etiology of neonatal seizures.
Pak Paed J Jan ;30(4):168-73.

Objective: To determine the incidence of seizures in admitted neonates and establish the etiological diagnosis. Patients: During the study period, 4.8% (97 cases) cases among admitted neonates, having seizures either at presentation or during their stay in the hospital, were included. Results: Hypoxic ischemic encephalopathy was found to be the commonest cause (44.3%) of neonatal seizures, followed by hypoglycemia (19.5%) and hypocalcemia (12.3%) cases. Subtle seizures (41.2%) were the most frequently observed type of seizure, followed by tonic (32.9%) and clonic (20.6%) seizures. Nearly 55% cases had seizures during the first 48 hours of life. Cases of hypoxic ischemic encephalopathy were associated with higher mortality (39.5%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found as a common neurological disorder and presented most commonly as subtle type. Birth asphyxia was the commonest aetiology of neonatal seizures, followed closely by the metabolic seizures.

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