Muhammad Ali Sheikh, Jamshed Akhtar, Tayyaba Batool, Rubab Naqvi, Raees Taqvi, Shazia Jalil, Aqil Soomro, Soofia Ahmed, Farhat Mirza.
A study of ovarian lesions in pre-menarche girls.
J Coll Physicians Surg Pak Jan ;17(3):162-5.

Objective: To analyze various clinical presentations and the surgical management of ovarian pathologies in pre-menarche girls. Design: Case series. Place and Duration of Study: Surgical Unit B, National Institute of Child Health, Karachi, from September 2002 to August 2004. Patients and Methods: Case records of all the pre-menarche girls child having an ovarian pathology and managed during the study period were reviewed. Age of the patients, presenting symptoms, investigations performed, surgical approaches, operative findings and final histological diagnosis were noted. Ovarian lesions were classified according to WHO criteria. System proposed by the Children`s Cancer Group and the Paediatric Oncology Group was used for staging of tumors. Following resection, patients with malignant tumors were followed-up by oncologist. Results: There were 18 patients with ovarian lesions. Age range of patients was from day 1 to 13 years. Mass in abdomen was the most common presenting symptom (60% patients ) followed by pain (50%). Right ovary was involved in 12 (55%) cases and left in 6 (45%). Six patients had non-tumorous cysts, 3 had benign tumors and 9 were with malignant lesions. Of the non-tumorous cysts, 3 patients had simple follicular cysts and 2 were hemorrhagic cysts. There were 2 patients with benign teratoma and one with dermoid cyst. Four patients had malignant teratoma, 4 dysgerminoma and one yolk sac tumor. Malignant tumors were all of stage IA according to Paediatric Oncology Group staging. Conclusion: Ovarian tumors are rare in paediatric age group especially in pre-menarche girls. Except one, all malignant tumors were found in patients above 7 years of age. Benign (tumorous and non-tumorous) and malignant lesions occurred with equal frequency in pre-menarche girls in this study.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com