Muhammad Akram, Mehrun Nisa, Muhammad Shafiq, Waqas Tariq Butt, Sohaib Tariq, Abdus Samad, Samad Saad.
The effect of fasting on QT Interval.
Ann King Edward Med Uni Jan ;13(1):116-8.

Introduction: QT interval reflects the total duration of ventricular depolarization and repolarization in the ECG. Experimental hypoglycaemia and spontaneous clinical episodes of hypoglycaemia lead to the lengthening of the heart rate corrected QT interval or QTc. This is associated with elevated risk of sudden death. Objective: To find out the effect of fasting blood glucose levels on QT interval and the corrected QT interval (QTc). Materials and Methods: Fasting and post prandial blood glucose levels and ECG of healthy young adults were studied and QT interval, RR interval and QTc were determined. Results: The fasting QTc came out to be 0.408+-0.020 as compared to the post prandial value of 0.380+-0.019. The student`s t test showed a highly significant value (p<0.0001). Conclusion: There is significant prolongation of QT interval and QTc during fasting but within normal physiological limits.

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