Miraj Mohammad Khan, Sahibzada Mahmood Noor, Khan Nawaz.
Single dose fluconazole in the treatment of pityriasis versicolor.
J Pak Assoc Derma Jan ;17(1):28-31.

Objectives: To evaluate the efficacy and safety of single dose (450mg) of fluconazole in the treatment of pityriasis versicolor. Patients and methods: Patients suffering from pityriasis versicolor presenting to department of dermatology, Hayatabad Medical Complex, Peshawar were enrolled in the study. Diagnosis of PV was made by Wood`s lamp and confirmed by examination of scales in KOH preparation. 30 patients were included in the study. Results: 30 patients completed the study including 24 males and 6 females. Their age ranged from 14 years to 45 years (mean 25.3 years). Eighteen patients (60%) had complete cure and their clinical and laboratory parameters remained negative at 3 weeks and 6 weeks after completion of treatment. Twelve (40%) had no response to treatment. Treatment was well-tolerated and there were no adverse affects reported with single 450mg of fluconazole. Conclusion: Fluconazole 450mg as a single dose was effective in the treatment of pityriasis versicolor and well tolerated. However, long term comparative studies should be done to establish the efficacy of fluconazole as a single dose treatment in PV.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com