Shabnam Naseer Awan, Shazia Nayyar, Nadeem Ashraf.
Obstetrics and perinatal outcome; risk factors for hepatitis B and C transmission.
Professional Med J Jan ;13(4):511-6.

Objectives: To identify and assess the risk factor for transmission of HBV and HCVpregnant ladies and perinatal outcome; presenting to obstetric OPD at CMH Lahore. Design: Case control Setting: Combined Military Hospital Lahore. Period: From May 2003 to April 2004. Patients and Methods: All the patients presenting to obstetrical OPD during one year were randomly screened for both hepatitis B and C using ELISA. Perinatal outcome was compared with control group. The risk factors for HBV and HCV were studied in 30 patients, who were positive for either HBV or HCV. A detailed history was taken followed by a questionnaire and screening for HBV and HCV. The results were compared with control group who were negative for hepatitis B and C but had same socioeconomic back ground and similar living conditions (wives and soldiers). Results: In the study group 20 patients gave history of surgical operation or dental procedure. These surgical operations included major or minor operations. In control group positive history of surgical or dental procedure was obtained in 12 patients. The odds ratio was found to be 3.00 with a P value of 0.038. History of blood transfusion was found in 12 patients in study group and 4 patients in control group with 0.019. Positive history of jaundice was found in 3 patients of study group and 1 patient in control group with p value of P>0.05. History of drug abuse or multiple sexual partners was negative in both groups. Conclusion: The study concludes that HCV infection is three times more common than HBV infection. Surgical procedures are the leading risk factors for acquisition of these infections.

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