Pervez Iqbal, Mohammad Saddique, Umairul Islam.
Leakage of colorectal anastomosis: experience at Civil Hospital, Karachi.
Pak J Surg Jan ;23(3):169-2.

Objective: To determine the frequency and outcome of leakage of Colorectal anastomosis. Design & Duration: A descriptive study from Jan. 1997 to Dec. 2003. Setting: Surgical Unit I and V of Civil Hospital, Karachi. Patients: One hundred and sixty four patients admitted with colorectal cancer, colon or rectal injury and those admitted for restorative procedures were included in the study. Methodology: Detailed history, physical examination and relevant investigation were carried out. Patients were operated by a senior surgeon. Patients were closely monitored after surgery for clinical signs of anastomotic leakage. CT scan was performed on the 10th postoperative day to ascertain the integrity of the anastomosis. Results: Colonic anastomosis was done in 118 cases with an anastomotic leak of 3.4% while rectal anastomosis was done in 28 patients with an anastomotic leak of 17.8% and a mortality of 10.7%. In most patients the average hospital stay after operation was 14 days. The overall anastomotic leak was 6.09% and mortality 2.4%. Conclusion: Colorectal anastomotic leakage is a serious complication. A high index of suspicion is required. Early diagnosis and prompt treatment are crucial in obtaining optimal results.

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