Transient acantholytic dermatosis was described by Grover. Its definite cause and pathogenesis is unknown. A 22-year-old man presented to our out-patient department with multiple itchy vesicles and pustules on the neck and chest. The biopsy was done and histopathology findings revealed focal acantholytic dyskeratosis. Case was diagnosed as Grover`s disease. Patient was given vitamin A 50000 IU per day and later dapsone was added. Patient was advised to avoid sunlight and heat. This is the first case of biopsy confirmed Grover`s disease from Nepal.
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