Balwant Rai, Simmi Kharb, Anand S C.
Effect of scaling and root planning on salivary 8- hydroxydeoxyguanosine levels : periodontitis.
J Pak Dent Assoc Jan ;16(4):189-91.

OBJECTIVE: Periodontal disease is an inflammatory disorder in which tissue damage occurs through complex interactions between periodontal pathogens and components of the host defense mechanisms and oxidative stress is implicated in pathophysiology. PATIENTS AND METHODS: Twelve subjects with periodontitis were selected and salivary samples were taken before treatment, after 3 weeks of treatment and after 10 weeks of the treatment for 8-OHdG levels (8- Hydroxydeoxyguanosine). RESULTS AND CONCLUSION: Salivary levels of 8-OHdG were significantly decreased with scaling and root planning. Thus, measurement of 8-OHdG may prove to be useful in identifying periodontal disease and risk of tooth loss.

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