Rid Hasan S M Farid, Fouzia Hassan, Sabahat Jabeen.
Studies on the quantification and comparison of dissolution profiles of two brands of Meloxicam tablets.
Pak J Pharmacol Jan ;24(1):43-51.

A simple model independent approach using a similarity factor (f2) and a difference factor (f1) to compare dissolution profiles as proposed by Moore and Flanner was used to evaluate the in vitro equivalence of two brands of meloxicam tablets. Our results showed that the two meloxicam formulations are not equivalent in vitro. Thus it is recommended that the same formulations should be evaluated to in vivo studies in order to find whether a co-relation exists between in vitro dissolution and in vivo bioavailability.

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