Molecular biology based assays are invaluable tools for the diagnosis and management of chronic viral hepatitis. They can be used to test donor`s blood, to diagnose active infection, guide treatment decisions, assess the virological response to therapy and establish the prognosis. For hepatitis C infection, these include serological assays for anti-HCV antibody detection and molecular assays that detect and quantify HCV-RNA and determine the HCV genotype. This article reviews the current molecular biology based techniques and assays and their practical use in the management of hepatitis C virus infection. This is a review article.
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