Nastaran Madjdinasab, Naser Sharafaddin Zadeh, Farhad Assarzadegan, Armaghan Moravej Ale Ali, Mohammad Pipelzadeh.
Efficacy comparison of splint and oral steroid therapy in nerve conduction velocity and latency median nerve in carpal tunnel syndrome.
Pak J Med Sci Jan ;24(4):725-8.

Objectives: To evaluate the effects of splinting in neutral position of the wrist and oral Prednisolone on neurophysiologic variables in patients with Carpal tunnel syndrome (CTS). Methodology: This double blind study was carried out in 48 idiopathic CTS patients. They were randomly divided in two groups. Splint group (N=24) used splint for six weeks; and steroid group (N=24) who got oral Prednisolone 20mg/day for two weeks. Electrophysiological evaluations were done initially for having baseline and after 1.5-months follow up. SPSS software (version 11) and independent T test and paired T test were used for statistical analysis. Results: After six weeks median nerve motor and sensory had distal latency and their conduction velocity improved significantly in both groups (P<0.05). There was no significant difference between both groups due to electro physiologic improvement and clinical improvement. Conclusion: There was significant electro physiologic improvement in both groups, at six weeks. On comparing the efficacy of the two treatment methods, there was no significant difference between the two.

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