Hana M Jamjoom.
Clinical efficacy and side effects of in-office and home bleaching treatments.
J Pak Dent Assoc Jan ;17(3):139-45.

This study investigated the effect of in-office and home bleaching agents on colour changes and tooth sensitivity. MATERIAL AND METHODS: We studied 50 mandibular and maxillar arches of 25 female subjects with a mean age of 24+3.9 years. They were divided into four groups: Subjects in group I used opalescent Xtraboost office bleaching for three intervals. Opalescence 20% (home bleaching; group II), Opalescent 15% (home bleaching; group III), and Nitewhite 16% (home bleaching; group IV) used for two weeks. Shades were assessed by the vita shade guide before treatment and at one week, two weeks, and three weeks interval after treatment for relapse of shade. Tooth sensitivity and gingival irritation were recorded. RESULTS: Using Wilcoxon signed ranks test, the change in colour from baseline to one and two weeks post treatment was significant in all groups. In-office bleaching had the same effect on colour change (60%) and showed significant tooth sensitivity as group III. Group IV had the least effect, with (40% colour change, (40%) increase in tooth sensitivity, and gingival irritation, although it had the longest application time 63 hours. Group II had the best result of (77.7%) colour change with no tooth sensitivity or gingival irritation. CONCLUSION: Home bleaching with 20% concentration was the most effective of all groups. Office bleaching had the same effect on colour change and tooth sensitivity as 15% home bleaching. Nitewhite was the least effective and was highly irritant.

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