Khurshid Shabbir Raja, Huma Tasleem.
Effects of uterine leiomyoma on the course of pregnancy and labor.
Rawal Med J Jan ;34(1):79-81.

Objective To evaluate the effects of uterine leiomyoma on the course of pregnancy, mode of delivery and frequency of complications during pregnancy and labour. Method Fifty booked antenatal patients having uterine leiomyoma were studied during a period of two years. Results Out of fifty patients, thirty (62 %) had no significant change in the size of myoma throughout gestation. Eleven (22 %) had abortion, seven (14 %) developed premature rupture of membranes and five (10 %) went into preterm labour. Red degeneration occurred in two patients (4 %). Abnormal presentation occurred in six patients (12 %). Fifteen patients (30 %) remained asymptomatic throughout pregnancy. Out of 50 patients, 37 patients (74 %) remained asymptomatic during labour. Twenty one (53.8 %) were delivered vaginally and caesarean section had to be performed in eighteen (46.1 %) patients. Conclusions Uterine leiomyoma may adversely affect the course of pregnancy and labour depending on their location and size. The changes in size during pregnancy have no significant effect on the course of pregnancy. (Rawal Med J 2009; 34: 79-81).

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