Syed Intesar Mehdi Kazmi, Syed Hussain Mehdi, Farooq Umar.
Frequency and pattern of advanced breast cancer at Abbasi Shaheed Hospital.
Pak J Surg Jan ;25(1):3-5.

Objective: To describe the frequency, presenting features and distribution by stage of Advanced Breast Cancer. Study Design: Case series. Setting & Duration: Abbasi Shaheed Hospital, Karachi from December 1999 to December 2000. Methodology: This was a descriptive study aimed at determining the frequency of advanced cases of breast cancer at Abbasi Shaheed hospital. Female patients presenting at the out patient department and later diagnosed as advanced breast cancer were included. Final histopathology was taken as the gold standard for categorizing locally advanced disease, while metastatic cancer was determined on the basis of clinical, laboratory and radiological data. Cases of recurrence (local or metastatic) were excluded. Results: A total of 27 cases of breast cancer were diagnosed during the study period. Of these, 18(66.6%) were found to have advanced disease. Locally advanced cancer (AJCC Stage III A and B) was found in 16(59.25%) patients, while only 2(7.4%) had metastasis at the time of presentation. Conclusion: Frequeny of advanced carcinoma in this study in younger population in higher compared to previous data.

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