Tasneem Ashraf.
Pap smear.
Professional Med J Jan ;11(4):461-5.

To detect and manage Pre-cancerous cervical change in order to prevent invasive cancer in a symptomatic sexually active women of reproductive age group. Study design: An observational study. Place and duration of study: Study was conducted in Gynae unit 11 of Bolan Medical College Complex Quetta from June 2002 to May 2004. Patients and Methods: 370 women visiting either Gynae OPD or antenatal clinic were included in study. Positive smears were followed by biopsy and histopathology. Results: 198(53.51%) smears were reported to be normal, 126(34%) inflammatory, 20(5.40%) borderline, mild dyskaryosis was seen in 6(1.62%) moderate in 5(1.35%) and severe dyskaryosis in 3(0.81%). 14 smears were considered inadequate because of blood stained specimen or due to other artifacts. Patients with mild dyskaryosis were advised to come for follow up and to repeat smear after three months.8(2.16%) patients with moderate to severe dyskaryosis had punch biopsy. Histopathology revealed CIN-II in four cases of moderate dyskaryosis and CIN-III in one case of severe dyskaryosis. Two patients with moderate dyskaryosis were managed by local destructive procedure with electrocautry. While two patients with CIN-II and three patients with severe dyskaryosis had total abdominal hysterectomy due to continuous pain lower abdominal and excessive vaginal discharge. Conclusion: Cervical cancer screening by pap smear is a simple and effective method of detecting pre malignant lesions. If it is done routinely in asymptomatic patients at regular intervals, it may help to decrease the incidence of the invasive cancer.

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