Abbass Modir, Seyyed Mostafa Shiryazdi, Mohammad Hossein Ahmadie, Leila Nikookar.
Prevalence of breast cancer and positive predictive value of mammography among Yazd city Iran.
Pak J Surg Jan ;23(1):3-6.

Objective: To evaluate the prevalence of Breast Cancer amongst women in Yazd city and to determine the positive predictive value of mammography in the diagnosis of Breast cancer as compared to pathology. Design & Duration: Prospective, descriptive study using clustering sample technique. Setting: Department of Surgery, University of Yazd Medical School, Yazd, Iran. Patients: All women who consented to participate in this trial. Methodology: In this research 40 clusters of 35 households were randomly selected from the available list in Yazd City Health Center. They were approached through home visits, and one woman aged 30 years or above was invited to undergo mammography and examination at the Radiology Center in Bahman Hospital, Yazd. Cases reported positive for tumor or cancer, underwent FNAC or open surgery, after counselling. Results: A total of 916 (65.43%) women reported and had their mammographies performed; 305 (33.3%) cases turned out to be abnormal, while 38 (4.1%) cases were reported as malignant. However, histopathology report confirmed only 24 patients. Hence the incidence of breast cancer was estimated as 2.62% among women in Yazd city. The positive predictive value of mammography in comparison with pathology was 70.6%. Conclusion: The prevalence of Carcinoma Breast in Yazd city was 2.62%. Considering the high incidence of malig- nancy in the thirties it is suggested that screening with mammography should start at the age of 30 years, especially in women with history of family breast cancer).

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