Ismail A Khatri, Umar S Chaudhry.
Parkinson`s disease - a review.
Pak J Neurological Sci Jan ;4(1):33-43.

Parkinson`s disease is not only among the most common neurodegenerative disorders, it is also one of the most famed neurological illnesses with several celebrity figures suffering from Parkinson`s disease. Over the past few decades there has been steady increase in the understanding of disease pathophysiology and clinical course, with advances in management choices including new drug therapies, surgical treatment options and growing hopes in neurotransplantation and gene therapy. The rapid change in this arena makes it necessary for clinicians and students of neurology to come abreast with these advances. This becomes more informative if we also examine what we know from past. This article provides a concise yet meticulous review of Parkinson`s disease through a thorough literature review exploring all major aspects including epidemiology, etiology and pathophysiology, signs and symptoms, diagnostic evaluation, management including pharmacotherapy, and new modalities of treatment such as deep brain stimulation and neurotransplantation. Ongoing research is also outlined. (Review article).

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