Rafael Cincu, Juan F Martín Lazaro, Jose Luis Capablo Liesa, Jose Eiras.
Gliosarcoma: an uncommon brain tumor.
Pak J Neurological Sci Jan ;4(1):20-2.

Gliosarcomas are rare bimorphic intraaxial malignant neoplasms of the central nervous system. A 69-year-old gentleman presented with a history of right-sided weakness and slurred speech. Brain imaging (CT scan and MRI) was suggestive of a left fronto-parietal mass lesion with contrast enhancement at the periphery. Neuropathological examination revealed a malignant brain tumour presenting a biphasic tissue pattern with gliomatous and mesenchymal components suggestive of gliosarcoma that was further evaluated immuno¬histochemically. Although the treatment of gliosarcomas is almost similar to glioblastomas (surgical resection and, depending on clinical status, radiotherapy and/or chemotherapy) the prognosis of gliosarcomas remains poor.

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