Naheed Parveen, Rehana Majeed, Uzma D M Rajar.
Familial predisposition of dysmenorrhea among the medical students.
Pak J Med Sci Jan ;25(5):857-60.

Objective: To evaluate familial predisposition of dysmenorrhea among the medical students of Isra University Hyderabad. Methodology: An observational study was carried out at Isra University Hyderabad, from June to November 2007 in which a total number of 197 students participated.A pre designed questionnaire was administered to the female medical students in which their age, menarcheal age about menstrual cycle, presence or absence of dysmenorrhea, severity of symptoms and positive family history of dysmenorrhea in mothers and in sisters were asked. Exclusion criteria of the study were amenorrhea, irregular menstrual cycle and whose mothers and sisters had secondary dysmenorrhea as this study basically was concerned with primary dysmenorrhea and to observe familial risk. Results: In this study dysmenorrheal was observed in 76%, the mean age of students was 20.9 SD±1.7, mean age at menarche with dysmenorrhea was 13.2 SD±1.1 and without dysmenorrhea was 12.7 SD±0.9. Positive family history of dysmenorrhea was seen in 33% of mothers and 43% in sisters and there was a group of students who had positive history in both mothers as well as in sisters. Conclusion: We found significant correlation of positive family history with dysmenorrhea in the present study. This suggests that genetic factor is involved in the pathogenesis of primary dysmenorrhea and increases the familial tendency. Therefore positive family history could be the strong predictor for occurrence of dysmenorrhea in offspring and in siblings.

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