Razia Iftikhar, Waqas Ahmed Burney.
Role of misoprostol in inducing abortion in previous cesarean section.
J Surg Pak Jan ;14(3):120-3.

Objective: To determine the effectiveness of misoprostol in second trimester abortion in post caesarean cases in terms of complications and side effects. Study design Descriptive study. Place & Duration of study. Department of Obstetrics & Gynaecology, Baqai Medical University and Private Clinics, From January 2007 to January 2009. Patients and Methods. Fifty patients were selected for the study. Gestational age was between 14-20 weeks. They received 400 microgram of misoprostol tablets moistened with 2-4 drops of water intravaginally. Effectiveness was determined by the number of women who expelled fetus/product of contraception without the need for surgical intervention in a previously scarred uterus. Results: Patients in the study group underwent termination of pregnancy for missed abortion (n 32), foetal anomaly (n14) and foetal demise (n 4). The median induction-abortion interval was 16 hours (range 10-21 hours). Misoprostol was found to be safe in our cases of post caesarean women and there was no case of scar rupture or dehiscence, haemorrhage and shock. Conclusions: The use of misoprostol to mid trimester abortion is a type of day care abortion and not contraindicated in women with previous scar uterus in terms of complication and side effects.

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