Ghazala Hanif, Samina Zaman, Mahvish Hussain, Nasir Mahmood, Anum Shahid, Ayesha Ghazal.
Clinico-morphological pattern of bone lesions in children.
Biomedica Jan ;25(1):59-62.

The present study was performed to find the spectrum of bone diseases in children and to correlate with age, sex, and site of origin. This was a retrospective study and consists of 95 cases of bone biopsies which were diagnosed in the Department of Pathology at the Institute of Child Health and Children’s Hospital, Lahore during a period of six years (Jan 2003-Dec 2008). These biopsies were evaluated on haematoxylin and eosin stained sections from paraffin embedded tissue blocks. Special stains were performed whenever required. Pyogenic osteomyelitis (OM) accounted for 35.78% of all bone pathologies followed by tuberculous osteomyelitis in 22.10%. Osteosarcoma (OS) was the most frequent (primary tumour of bone followed by Ewing’s sarcoma (ES). One case of metastatic bone tumour was also recorded. Osteochondroma, osteoma, aneurysmal bone cyst, fibro-osseous dysplasia, chondroma and simple bone cyst were also found in children. The bone tumours are relatively more prevalent in males.

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