Khemchand N Moorani, Sadaf Asim, Saeed Hassan Chishty, Afroze Ramzan Sherali.
Outcome of pediatric renal biopsy with monopty gun technique.
J Surg Pak Jan ;15(1):9-14.

Objective: To determine the outcome of percutaneous renal biopsy (PRB) using Monopty-gun technique (MGT) and to compare the results of sedation with general anesthesia (GA) used for the procedure. Study design: Descriptive study. Place & Duration of study Department of Pediatrics at National Institute of Child Health (NICH) and the Kidney Center Postgraduate Training Institute (KPTI), Karachi from June 2005 to February 2010. Methodology: Renal biopsies were performed either under sedation / GA at NICH and KPTI respectively using MGT under ultrasound guidance (USG) after routine tests. A resident / nurse monitored the procedure. Data including age, sex, indication, vitals monitored, number of attempts per patient, glomeruli per biopsy and complications were recorded. Using Statistical-Package-Scientific- Software (SPSS) version-15, descriptive statistics were applied. Paired test was used to compare pre-and-post procedure vitals. P<0.05 was considered significant. Results: A total of 147 biopsies in 145 children were performed. Boys were 79(54.48%) and girls 66(45.51%). Mean age was 7.31+4.23 years Most of the procedures were performed under sedation (n 105, 71.42%). Indications were nephrotic syndrome (NS) in 96(65.3%), secondary glomerulonephritis (SGN) in 17(11.6%), nephritic-nephrotic syndrome (NNS) in 16 (10.9%), congenital nephrotic syndrome (NS) in 15(10.2%) and others 3(2.06%). The success and adequacy rate was 95.91% and 95.23% respectively. Failure occurred in 5(3.4%) cases. Overall, 26(17.68%) complications were observed in 21(14.28%) patients with 6(4%) being major. Technique related complications (20, 76.92%) were more than sedation/GA related (SGRC - n 6,23%). The complications were more in sedation but the outcome was better in GA. Conclusions: MGT is a safe for PRB in children. The success, adequacy and complication rates in our study are in uniformity with the current standards.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com