Fakhar Shareeq, Shehnaz Yousuf.
Early Detection of Complete Hydatidiform Mole in high risk group by measuring Maternal Serum Alpha-Fetoprotein.
J Coll Physicians Surg Pak Jan ;7(2):47-8.

Maternal serum alpha-fetoprotein (MS-AFP) levels were estimated by enzyme-linked immunosorbent assay (ELISA) on 144 subjects of whom 40 formed the control group. The subjects were 14-20 weeks pregnant and their ages were between 20 and 40 years. One hundred and four subjects were in a high-risk group of whom 100 had higher MS-AFP levels than the control group while 4 had MS-AFP levels lower than the control group. These 4 subjects had complete hydatidiform mole and their ultrasound scan showed `snow storm` appearance.

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