Mazharul Hassan, Umair Qidwai, Azizur Rahman, Niamatullah Sial, Nasir Bhatti.
Visual outcome after intravitreal bevacizumab injection in macular edema secondary to central retinal vein occlusion.
Pak J Ophthalmol Jan ;27(2):84-8.

Objective: To evaluate visual outcome after intra-vitreal Bevacizumab in macular edema secondary to central retinal vein occlusion. Materials and Methods: This prospective study was performed at Isra Postgraduate Institute of Ophthalmology, Al-Ibrahim Eye Hospital, Malir, Karachi. Patients with macular edema secondary to central retinal vein occlusion, ischemic and non-ischemic were selected from 1st February 2009 to 31st July 2009, by using non-probability purposive sampling technique. Informed written consent was taken from the patients. Best-corrected visual acuity was checked before giving the intra-vitreal Bevacizumab injection and after 1st, 4th and 12th week. Results: Out of 41 patients included in the study 32 patients (78 %) showed visual improvement of at least one line on Snellen visual acuity chart (P value of <0.05), while rest of the 9 patients (22 %) did not show visual improvement. Conclusion: Intra-vitreal Bevacizumab injection results in modest visual improvement in patients with macular edema due to central retinal vein occlusion.

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