Muhammad Tayyab, Mahmud Aurangzeb, Abid Hussain, Nafees Ahmad.
The prognostic factors in typhoid ileal perforation.
J Med Sci Jan ;18(2):79-82.

Objectives: To determine various prognostic factors and to evaluate their role in the outcome of surgical treatment of typhoid ileal perforation. Materials and Methods: The study was conducted in Surgical Department of Khyber Teaching Hospital, Peshawar from February 2005 to January 2006. Fifty patients with suspected typhoid ileal perforation and confirmed at operation were included in the study. Attention was paid to pre-operative, per-operative and post-operative factors which had a strong effect on the outcome of surgical treatment of typhoid ileal perforation. Results: The age range was 15-64 years (mean age = 33.5 years) with male to female ratio of 2.3:1. Most of the patients presented in 3rd week of their illness and were operated upon with a mean interval of 34.8 hours between perforation and operation. A total of 8 patients developed complications. Wound sepsis, a common complication in our study occurred in 4 patients, sub-phrenic abscess in 2 patients while re-perforation occurred in only one patient. All of them had presented late with a long history of chronic illness. No mortality was recorded in our study. Conclusion: The study concluded that surgical treatment of typhoid ileal perforation showed good results in those patients who were in satisfactory health with a short history of illness before perforation. In addition early surgical intervention and satisfactory per-operative findings had significant effects on post-operative outcome.

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