Muzamil Shahzad, Amer Iqbal, Azmat Khan.
To find out the relationship between liver cirrhosis and pulmonary fibrosis.
Pak J Med Health Sci Jan ;4(4):304-7.

Objective: To find out the relationship between cirrhosis of liver and pulmonary fibrosis in different cirrhosis groups according to child's classification. Study design: It is a descriptive study Place of study & duration of study: Medical Department at Social Security Hospital, Lahore during the period of six months from 01-01-2010 to 30-06-2010. Results: Prevalence of hepatitis C is more than hepatitis B. The causes of cirrhosis are the same as those of fibrosis. In developed countries, most cases result from chronic alcohol abuse or chronic hepatitis C. In parts of Asia and Africa, cirrhosis often results from chronic hepatitis B. Pulmonary fibrosis is a major component of many interstitial, or diffuse parenchymal, lung diseases. Fifty patients included in this study between 20-75 years of age with mean±SD 36.67±8.35. Fifty six percent were male patients and 44% were female with male to female ratio 1.27:1. Child group A had 22 (44%) patients with mean±SD 1.52±0.29, group B 9 (18%) patients with mean±SD 1.02±0.62 and Child group C was 18(38%) respectively with mean±SD 1.31±0.21 and only 1 (2%) patient was missing. The Child’s class A had 9(18%) patients, Child’s class B 16(32%) and Child’s class C had 22(44%) patients respectively. Child’s class was assigned to each patient based on two clinical and three laboratory criteria as defined in CTP system. Out of 50 patients 22(44%) were present of pulmonary fibrosis in cirrhosis based on clinical and laboratory criteria. Twenty six (52%) were absent and only 2(4%) were missing due to incomplete workup. The ultrasonography finding on features of portal hypertension i.e. reduced liver span 50(100%) were present and portal vein dilation were 10(20%) were present, while 6(12%) were absent splenomegaly were 9(18%) patients were present and 5(10%) were absent and ascities were 13(26%) patients present and 4(8%) were absent. Pulmonary fibrosis and cirrhosis of liver were statistical correlation test difference was significant (p <0.05). Conclusion: A significant relationship between liver cirrhosis and pulmonary fibrosis and with advancement of Child’s class, frequency of pulmonary fibrosis increases.

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