M Naeem Khan, Mansoor Nadeem, M Ayyub, M Farooq Khattak, M Anwar, Azmat Rashid, Karamat Ahmed Karamat.
Lupus anticoagulant: A cause for stroke in young adults.
Pak J Pathol Jan ;10(2):4-6.

The lupus anticoagulant (LA) belongs to family of immunoglobulins, most commonly an IgG isotype. These antibodies have been identified in association with thromboembolic disease. We studied 52 patients of both sexes presenting with stroke before the age of 45 years for presence of lupus anticoagulant. Of these 24 were female and 28 were male. Computed tomography scan of skull was performed in every case and only the patients with thrombotic stroke were included in this study. Four (7.69%) of 52 patients were found to have positive test for LA which is a significant finding.

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