Nayek K, Ghosh T N, Chattopadhyay T K, Ghosh N, Banerjee A, Saha I.
Clinicoetiological profile and drug sensitivity patterns of urinary tract infections in paediatric patients attending a rural tertiary care hospital.
Pak Paed J Jan ;35(4):220-5.

Introduction: Urinary Tract Infections (UTI), one of the most common childhood infections warrants early diagnosis as it causes renal damage by renal scarring leading to end stage renal disease. Diagnosis is often difficult as it is associated with a wide spectrum of clinical features. Adequate treatment of UTI depends upon knowledge of the local pattern of causative organism along with their drug sensitivity. This study is carried to identify the clinical features associated with UTI, along with its causative agents and their drug sensitivity. Materials & Methods: Children presenting with symptoms of fever, dysuria, crying during micturation, hematuria, history of dribbling, abdominal pain, increased frequency, straining during voiding were subjected to urine culture to diagnose UTI. Drug susceptibility was carried out on specimens positive for UTI. Results: Among the 147 patients investigated, 43% were positive for urine culture. Increased frequency was the chief complaint in age groups of < 1yr and 4-7 yrs, where as fever was most common in age group of 1-4yr and ≥7yrs. Escherichia Coli was the most frequent pathogen isolated. Cephlexin and Co Trimoxazole were the most resistant drugs whereas Amikacin was most sensitive. Conclusion: UTI should be diagnosed early and adequately treated to prevent renal damage. There is high prevalence of drug resistant urinary pathogens. Empirical antibiotic selection should be based on knowledge of the local prevalence of bacterial organisms and antibiotic sensitivities rather than on universal guidelines.

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