Mohammad Shoaib Khan, Rafat Ullah, Fahim Tahir, Mohammad Ashraf, Mohammad Sajjad.
Seminal volume in the investigation of male infertility.
J Coll Physicians Surg Pak Jan ;22(3):159-62.

Objective: To determine the seminal volume among infertile males and the frequency distribution of hypospermic and hyperspermic patients in infertile males. Study Design: Cross-sectional observational study. Place and Duration of Study: Department of Reproductive Physiology/Health, Public Health Laboratories Division, National Institute of Health, Islamabad, from 2002 to 2009. Methodology: Semen examinations of infertile male were carried out according to the standardized method of the World Health Organization. Seminal volume of 2-6 ml were considered normal, while volumes less than 2 ml and higher than 6 ml were considered hypospermic and hyperspermic respectively. Results: Out of 1521 patients, 355 were hypospermic (23.34%), 1046 were normospermic (68.78%) while 120 were hyperspermic (7.88%). In the hypospermic cases, 57 out of 355 (16.05%) had a volume of less than 1 ml. Of those 57 patients, 34 were found to be azoospermic, 12 were asthenozoospermic, one each were terato and polyzoospermic, while 6 had normal counts. Among the hyperspermic patients (n=120), 3 were azoospermic, 24 were oligozoospermic and 19 cases (15.84%) had count within the normal range, while 1 patient was polyzoospermic. Significant differences (p < 0.05) were observed among azoospermic, oligoasthenozoospermic and teratozoospermic groups when comparing hypo and hyperspermic patients. Conclusion: Seminal volume is an important parameter for assessment of infertility investigation and its abnormalities constitute a valuable index of problems with the male partner, even if the count and motility are well within the acceptable limits.

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