Jovaria Mannan, Muhammad Naveed, Attia Kalim.
Developmentally delayed children with hand flapping and frequent paroxysms of laughter.
Pak Paed J Jan ;36(1):41-4.

Case history of young couple who came for antenatal advice with their two children who were developmentally delayed, having hand flapping, frequent paroxysms of laughter and puppet like gait, these unique features were clue to diagnosis, their chromosome 15 study showed deletion in 15q11.2-q13 and confirmed diagnosis of Angelman syndrome .

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com