Nasir Bhatti, Umair Qidwai, Umer Fawad, Munawar Hussain, Azizur Rehman, Mazharul Hasan.
Side effects and effectiveness of subconjunctival bevacizumab injection in patients with corneal neovascularization.
Pak J Ophthalmol Jan ;28(1):33-7.

Purpose: To evaluate the side effects and effectiveness of subconjunctival bevacizumab injection in reducing corneal neovascularization Material and Methods: Patients selected according to inclusion and exclusion criteria were randomly allocated to either group 1 (patients were given subconjunctival bevacizumab injection) and group 2 (patients were given subconjunctival sham injection), its effectiveness in the form of decrease in neovascular area and side effects were compared between the two groups. Results: 41 patients were included in each group. There was no statistical significance between the 2 groups in effectiveness of the subconjunctival injection as well as in the complications except decrease in the fibrinogen level which was observed in group 1. Conclusion: Subconjunctival bevacizumab injection failed to show significant improvement in either corneal neovascularisation or visual acuity.

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