Nadira Mamoon, Rabia Zafar, Iram Niaz, Khurram Mahmood, Saad, Tahir Ahmad.
Primary intraosseous solid carcinoma of the mandible: a case report and review of literature.
Biomedica Jan ;28(1):109-13.

A primary intraosseous carcinoma (PIOC) arising de-novo is an extremely rare tumour that is limited to the jaws. The majority of the reported cases of PIOC have their origin from the odontogenic cysts, those arising de-novo are rarely illustrated. The definite diagnosis of PIOC is often difficult as the lesion must be differentiated from other primary and metastatic squamous cell carcinomas of jaws. We report an uncommon case of PIOC arising de-novo in a 25 years old man. The clinical, radiological and histological features are described. This infrequent lesion should be considered in the differential diagnosis of any jaw radiolucency.

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