Siddique M, Sadiq H Malik, Tariq Mahmud Arain, Asma Shaukat, Tabinda Yasmin, Ahmad Sajid.
Frequency of infantile pyloric stenosis and ocular abnormalities in turner's syndrome in Bahawalpur city.
Biomedica Jan ;28(1):7-9.

Background: Turner’s syndrome is one of the most common of all chromosomal abnormalities. Pyloric stenosis is the most common pediatric surgical disorder of infancy that requires surgery for associated emesis.4 Ocular abnormalities are common in turner’s syndrome, but are under estimated and often neglected. Materials and Methods: The study that was hospital – based observational, was conducted from September 1st, 2005 to August 31, 2011 in the Al-Noor Hospital Yazman (Bahawalpur) in collaboration with ophthalmology department, Bahawal Victoria Hospital Bahawalpur. Laboratory investigations including electrolytes, blood gas analysis, and osmolality were done in pathology department, Quaid-e-Azam Medical College Bahawalpur. Results: Frequency of pyloric stenosis in infants from 0 – 6 months 64.95% and infants 6 – 12 months is 35.09%, the ocular abnormalities amblyopia 19%, strabismus 23%, phoria only 43.5%, epicanthus 10%, hypertelorism 3%, ptosis 1%, nystagmus 0.5%. Conclusions: There is a high frequency of ocular abnormalities and pyloric stenosis in infants with karyotye XO. Timely diagnosis may save from devastating effects of ocular complications leading to blindness and life threatening alkalosis due to pyloric stenosis in infants below one year of age.

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