Abdul Hafeez Baloch, Salma Farrukh Memon, Asmat Kamal Ansari.
Comparison of placentae from hypertension associated pregnancies and normal pregnancies.
J Liaquat Uni Med Health Sci Jan ;11(1):03-6.

OBJECTIVES: This study was carried out to compare the placentae from hypertension associated pregnancies and normal pregnancies DESIGN: Comparative study SETTING: Isra University Hospital Hyderabad Sind. METHOD: Eighty full term placentae were collected; 40 from normal and 40 from hypertensive pregnant women. Gross features of placentae were noted and then stained for their microscopic features. Birth weight and Apgar score of the newborn were recorded. RESULTS: The weight and surface areas of placentae were significantly low in the hypertensive group whereas thickness of placenta and number of cotyledons were almost same in hypertensive and control groups. Microscopically increased number of syncytial knots, chorionic villi with excessive collagen was observed in placentae of hypertensive women. In hypertensive group birth weight of neonates was significantly low than control group while difference in APGAR score between two groups was statistically insignificant. CONCLUSION: Hypertension during pregnancy is associated with remarkable changes in the placentae.

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