Shahid Azeem Mirza, Amir Hussein, Arif Memon, Asad Azeem Mirza, Abdullah.
Safety and efficacy of lodoxamide 1% and sodium chromoglycate 4% in patients with vernal keratoconjunctivitis.
Pak J Surg Jan ;28(3):208-12.

Objective: To compare the severity of the disease after seven days treatment with Lodoxamide 0.1% ophthalmic solution eye drops with cromolyn sodium 4% eye drops in patients with bilateral VKC witheach follow up till 12 weeks. (90 days). To compare the type and severity of complications after the two drugs 12 weeks follow ups. Study Design: Quasi experimental , Interventional Setting : This study was carried out in the outpatient department at Jinnah Medical College Hospital, Karachi from February 2007 to April 2009. Subjects : Non Probability purposive Intervention : This comparative study was 12 weeks (three months) with each follow up after two weeks. Results: 60 patients between 5 to 18 years examined and selected for study. The patients were randomly divided into equal groups (30 patients in each group) with A and B. Group A received topical Lodoxamide ophthalmic solution 0.1% (LOS): Group B prescribed topical cromylin sodium ophthalmic solution 4% (CSO) in dose of two drops four times daily. Conclusions: From our study it can be concluded that vernal conjunctivitis is a disease of unknown etiology and is self limiting upto age of 18 years in majority of cases. No treatment is curative but we can make the patients symptom free as much as possible and can prevent its complications.

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